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World's first device-based treatment for small abdominal aortic aneurysms based on revolutionary new treatment paradigmbroad

STAAART SmarT Abdominal Aortic AneuRysm Treatment · Horizon Europe grant · 2024-01-01–2025-12-31

EC contribution

€2,499,999

Total cost

€3,999,674

Beneficiaries

1
About the data

Source: CORDIS (official EU open data), Horizon Europe. Framework HORIZON · call HORIZON-EIC-2023-ACCELERATOR-01 · scheme HORIZON-EIC-ACC-BF · topic HORIZON-EIC-2023-ACCELERATOROPEN-01. CORDIS record →

Objective

The Angiolutions device is a first-of-its-kind device stopping the life-threatening progression of small abdominal aortic aneurysm (AAA) – a pathological dilation of the aorta.Angiolutions’ award-winning & patent-protected solution leverages a fundamentally new understanding of AAA growth discovered by the founders at Stanford University. They showed that stiffness gradients between the compliant (healthy) aorta and the adjacent stiff (diseased) aneurysm serve as a motor for AAA growth.Based on this principle & together with key physicians, we developed a minimally-invasive, non-active aortic implant (class III). The nitinol-based device is positioned adjacent to the aneurysm sack via simple, catheter-based implantation. It is specifically designed to focally increase aortic stiffness in the compliant AAA neck region, thereby reducing stiffness gradients towards the stiff AAA sack that drive aneurysm growth.Hereby, we achieve a fast, low-risk, size-stabilizing treatment of small AAA.

Beneficiaries (1)

OrganisationCountryRoleEC contributionSME
ANGIOLUTIONS GMBH DE coordinator €2,499,999 Yes

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