DFM Funding Monitor

Next-generation heart bypass grafts to naturally restore cardiovascular function.broad

HeartRestore · Horizon Europe grant · 2022-12-01–2025-11-30

EC contribution

€2,481,701

Total cost

€4,205,284

Beneficiaries

2

About the data

Source: CORDIS (official EU open data), Horizon Europe. Framework HORIZON · call HORIZON-EIC-2021-ACCELERATOROPEN-01 · scheme HORIZON-EIC-ACC-BF · topic HORIZON-EIC-2021-ACCELERATOROPEN-01. CORDIS record →

Objective

Coronary Artery Disease is caused by narrowing of heart arteries that supply blood, often due to atherosclerosis. Coronary artery bypass grafting (CABG) is the gold standard surgery to treat it, and it commonly involves harvesting patient’s veins from the legs as grafts. This collection affects patients causing chronic pain and costly complications. It also has a high failure rate with >20% implants occluded after 1 year.Xeltis has developed a unique restorative vascular graft (XABG) that eliminates the need for vein harvesting. The implant provides a homing structure for cells in which cardiac and vascular tissues can be naturally restored, with the related advantages and benefits for patients and the healthcare system. We have proven our technology in first niche applications, as well as completed pre-clinical studies successfully for XABG. Now, we plan to perform a full clinical validation to obtain a CE mark in Europe and start market deployment and commercial up-scaling.

Beneficiaries (2)

Organisation	Country	Role	EC contribution	SME
XELTIS BV	NL	coordinator	€2,481,701	Yes
XELTIS AG	CH	thirdParty	€0	Yes

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