Opioid-free Pain relief for Enhanced Recovery After Spine fixation surgerybroad
OPERAS · Horizon Europe grant · 2023-04-01–2026-03-31
EC contribution
Total cost
Beneficiaries
About the data
Source: CORDIS (official EU open data), Horizon Europe. Framework HORIZON · call HORIZON-EIC-2023-ACCELERATOR-01 · scheme HORIZON-EIC-ACC-BF · topic HORIZON-EIC-2023-ACCELERATOROPEN-01. CORDIS record →
Objective
There is a troubling lack of effective pain treatments after major surgery. Especially after musculoskeletal procedures, patients experience debilitating pain now treated with opioids. Opioids provide insufficient pain relief, have many toxic side-effects, and are highly addictive. Pain and opioid-related side-effects impede early mobilisation and recovery and are the primary reasons for extended hospital stays.SentryX is developing revolutionary drug delivery technology to extend the effects of a well-established local pain blocker called bupivacaine. Its initial use case in spine fixation surgery, Bupi-Ring, delivers bupivacaine directly to the surgical site for more than 72 hours without changing the existing surgical workflow. Non-opioid local pain relief in this critical early phase of recovery will promote early mobilisation, shorten hospital stays, prevent complications, and save costs. This project will demonstrate Bupi-Ring’s safety and efficacy in humans for the first time.
Beneficiaries (1)
| Organisation | Country | Role | EC contribution | SME |
|---|---|---|---|---|
| SENTRYX BV | NL | coordinator | €2,500,000 | Yes |
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