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Next generation Limited-Angle time-of-flight PET imagerbroad

PetVision · Horizon Europe grant · 2023-09-01–2028-08-31

EC contribution

€3,374,041

Total cost

€3,374,041

Beneficiaries

9
About the data

Source: CORDIS (official EU open data), Horizon Europe. Framework HORIZON · call HORIZON-EIC-2022-PATHFINDEROPEN-01 · scheme HORIZON-EIC · topic HORIZON-EIC-2022-PATHFINDEROPEN-01-01. CORDIS record →

Objective

Over 2.7 million people in the EU were diagnosed with cancer in 2020, while 1.3 million people lost their lives to it. Cancer cases are predicted to increase by 24% by 2035, making it the leading cause of death in the EU. The current leading specific molecular imaging diagnostic technique sensitive to cancer is based on Positron Emission Tomography (PET). Due to the high implementation cost of PET, this high-sensitivity diagnostics, is only available to less than 0,5 % of the medical centers in the world. The critical component of the overall cost is the cost of PET scanners. Our project proposes a radical vision to translate European breakthrough technological advances in Time-of-Flight PET detection to a revolutionary, fully modular, cost-accessible flexible family of devices for applications from the standard PET center to the surgery, epilepsy clinics, intensive care units and even emergency rooms and in mobile units installed in vans. The proposed PetVision project aims to develop a simple pilot demonstrator, a modular panel PET device with a coincidence timing resolution of about 75 ps FWHM, close to the intrinsic timing limit of currently available PET scintillators. This resolution is several times better than the current gold standard of 214 ps FWHM achieved with the current clinical state-of-the-art device (Siemens Biograph Vision). With such excellent timing, the panel detectors can cover only a limited solid angle to reach the same sensitivity or improve the sensitivity in the case of a total-body imager. For the realization of the device, a package of breakthrough innovations in detector design, photo-sensor, and front-end electronics are planned. We expect that the proposed device will dramatically impact human health.

Beneficiaries (9)

OrganisationCountryRoleEC contributionSME
INSTITUT JOZEF STEFAN SI coordinator €832,183
FONDAZIONE BRUNO KESSLER IT participant €1,074,163
UNIVERSITAT DE BARCELONA ES participant €766,289
GENERAL EQUIPMENT FOR MEDICAL IMAGING SA ES participant €313,125 Yes
AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS ES participant €211,250
KLINIKUM DER TECHNISCHEN UNIVERSITÄT MÜNCHEN (TUM KLINIKUM) DE participant €177,031
THE GENERAL HOSPITAL CORPORATION US associatedPartner
ORGANISATION EUROPEENNE POUR LA RECHERCHE NUCLEAIRE CH associatedPartner
YALE UNIVERSITY US associatedPartner

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