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Enlisting synthetic fungal-bacterial consortia to produce multi-cellular mycelium-based ELMs with computational capabilitybroad

Fungateria · Horizon Europe grant · 2022-11-01–2026-10-31

EC contribution

€3,857,067

Total cost

€3,857,068

Beneficiaries

7
About the data

Source: CORDIS (official EU open data), Horizon Europe. Framework HORIZON · call HORIZON-EIC-2021-PATHFINDERCHALLENGES-01 · scheme HORIZON-EIC · topic HORIZON-EIC-2021-PATHFINDERCHALLENGES-01-05. CORDIS record →

Objective

Fungateria addresses a development gap in mycelium-based ELMs by developing a portfolio of ELMs that are composed of a synthetic co-cultivation consortium of a filamentous fungus and a bacterial strain. Sensing and adaptive growth of the fungal hyphae are exploited to develop an autonomous bottom-up and scalable manufacturing technology called Growth Composing (GC) that enables an engineered morphogenesis of mycelium materials using robotically controlled spray nozzles that generate local air, gas or aerosol flows steering hyphal growth. In addition, bioprinting is used to deposit inocula of the engineered bacterial strain in specific patterns and at specific times throughout the production process. Various ELM products are developed, ranging from consumer goods to applications in the environmental and construction sector, which become active through environmental cues of light, temperature and chemical attractants. To this end, synthetic biology engineering will be implemented to use the bacterial strain as a chassis for sensor-containing genetic circuits that render advanced functionalities to the ELM throughout its life cycle, either through direct activity or by influencing growth and morphology of the fungal partner. ELM activity is verified with probes that reveal bio-electric signaling in the materials - providing additional dimensions of control, monitoring, functionality and exploitation as actively computing devices. When no longer needed or having reached the end of their productive life, kill switches are activated either by human-controlled environmental triggers or triggers of the system itself, thereby causing the ELM to fully and quickly degrade without causing any negative environmental impact. Throughout the Fungateria project, a societal dialogue will be established to continuously align research objectives with ethical and regulatory requirements.

Beneficiaries (7)

OrganisationCountryRoleEC contributionSME
DET KONGELIGE DANSKE KUNST-AKADEMISSKOLER FOR ARKITEKTIR, DESIGN OG KONSERVERING DK coordinator €845,376
UNIVERSITEIT UTRECHT NL participant €651,146
UNIVERSITEIT GENT BE participant €642,500
VRIJE UNIVERSITEIT BRUSSEL BE participant €618,000
UNIVERSITETET I OSLO NO participant €600,048
DIMOKRITIO PANEPISTIMIO THRAKIS EL participant €499,998
UNIVERSITY OF THE WEST OF ENGLAND, BRISTOL UK associatedPartner

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