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BIOTECHNOLOGICAL ENGINEERING IN CULTIVATED CITRUS SPECIES FOR MULTIPLE STRESS TOLERANCE AND ENHANCED NUTRACEUTICAL PROPERTIESbroad

CitrusAId · Horizon Europe grant · 2026-10-01–2030-09-30

EC contribution

€3,987,807

Total cost

€0

Beneficiaries

11
About the data

Source: CORDIS (official EU open data), Horizon Europe. Framework HORIZON · call HORIZON-EIC-2025-PATHFINDERCHALLENGES-01 · scheme HORIZON-EIC · topic HORIZON-EIC-2025-PATHFINDERCHALLENGES-01-01. CORDIS record →

Objective

The CitrusAId project aims to develop cutting-edge biotechnological tools to create improved citrus plants that can better withstand environmental stresses such as drought, heat, pest and diseases, while also offering enhanced nutraceutical properties through the enrichment of beneficial compounds and the reduction of undesirable ones. Citrus is one of the most widespread fruit crops worldwide with an important socioeconomic impact in the Mediterranean area. Central to the project is the use of artificial intelligence (AI) to analyze large-scale omics datasets and in-house resources, enabling predictive identification of promising gene candidates for targeted genetic engineering. Secondly, the proposal also aims to support innovative genetic engineering strategies (CRISPR/Cas9 and RNAi) based on the use of novel bionanomaterials as tunable carriers do deliver gRNA, dsRNA and Cas9 protein, enabling the generation of transgene free plant material. The research extends from the molecular to the organismal level: seedlings will be analyzed under stress conditions using phenotypic, transcriptional, metabolomic, and hormonal profiling, while fruits will be assessed for the enrichment in native (flavonoids) and non-native (stilbenes) nutraceutical compounds considering any potential side effects on sensory quality. Work plan of CitrusAId is structured into 11 complementary and interconnected work packages (WP) that combine AI-driven gene discovery, novel hybrid nanomaterials-based genetic engineering methodologies, automated phenotyping, and sustainability assessments, along with dissemination and management activities. CitrusAId consortium is constituted by 11 partners from Spain, France, Italy and Germany and the duration of the project has been established in forty-eight months, that enables CitrusAId to deliver a proof-of-concept of the efficacy of the developed technologies providing viable plants by the end of the project implementation.

Beneficiaries (11)

OrganisationCountryRoleEC contributionSME
UNIVERSITAT JAUME I DE CASTELLON ES coordinator €614,063
CONSIGLIO PER LA RICERCA IN AGRICOLTURA E L'ANALISI DELL'ECONOMIA AGRARIA IT participant €590,040
UNITEC SPA IT participant €382,438
CYBRES GMBH DE participant €376,000 Yes
CENTRE DE COOPERATION INTERNATIONALE EN RECHERCHE AGRONOMIQUE POUR LEDEVELOPPEMENT - C.I.R.A.D. EPIC FR participant €336,263
INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT FR participant €305,985
SVERIGES LANTBRUKSUNIVERSITET SE participant €298,069
INSTITUTO VALENCIANO DE INVESTIGACIONES AGRARIAS ES participant €279,976
COMPUTOMICS GMBH DE participant €275,738 Yes
FUNDACION EMPRESA UNIVERSIDAD GALLEGA ES participant €266,562
DORIANE SAS FR participant €262,675

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