BioFunctional IntraNeural Electrodesbroad
BioFINE · Horizon Europe grant · 2023-04-01–2026-09-30
EC contribution
Total cost
Beneficiaries
About the data
Source: CORDIS (official EU open data), Horizon Europe. Framework HORIZON · call HORIZON-EIC-2022-PATHFINDEROPEN-01 · scheme HORIZON-EIC · topic HORIZON-EIC-2022-PATHFINDEROPEN-01-01. CORDIS record →
Objective
BioFunctional IntraNeural Electrodes : In BioFINE we will develop flexible intraneural multielectrode arrays, capable of interfacing peripheral nerves e.g. to transfer input/output signals from bionic limbs. Specifically, we address the challenge of long term tissue integration and chronic stability, by addressing three aspects of biocompatibility: 1) We develop novel fabrication methods allowing the intraneural interface to be defined at even finer resolution than before; 2) we explore functionalizations which will control the tissue response by combined surface anchored and surface eluted agents; 3) we address structural biocompatibility on a system level by engineering novel implantable interconnects which reduced tethering forces and improve prospects for high channel count interfaces. Fine-tuned bioactivity will safe-guard surrounding neural tissue in the initial stages of healing, and implants of sub-cellular dimensions and tissue compatible biomechanics, will safe-guard tissue healthy in the longer term. The combined approach will offer optimal conditions to bridge the gap from electrode to neuron and generate a long term functional peripheral nerve interface. Indeed, each of the three technological advancements would on their own have substantial impact on neurotechnology, reaching far beyond intraneural interfaces.
Beneficiaries (4)
| Organisation | Country | Role | EC contribution | SME |
|---|---|---|---|---|
| CHALMERS TEKNISKA HOGSKOLA AB | SE | coordinator | €564,338 | |
| ALBERT-LUDWIGS-UNIVERSITAET FREIBURG | DE | participant | €509,375 | |
| UNIVERSITA DEGLI STUDI DI FERRARA | IT | participant | €469,014 | |
| UNIVERSITAT AUTONOMA DE BARCELONA | ES | participant | €402,895 |
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