Deciphering the role of host immunity in development of herpes virus meningitiscore
Divir · Horizon Europe grant · 2023-01-01–2024-12-31
EC contribution
Total cost
Beneficiaries
About the data
Source: CORDIS (official EU open data), Horizon Europe. Framework HORIZON · call HORIZON-MSCA-2021-PF-01 · scheme HORIZON-TMA-MSCA-PF-EF · topic HORIZON-MSCA-2021-PF-01-01. CORDIS record →
Objective
Viral infection remains a major health burden globally, particularly considering the recent emerging viruses. The reason why individuals differ in susceptibility to viral infection is an essential, still unresolved question, in infection immunology research. The answer has strong impact on understanding of fundamental immunological principles as well as clinical medicine.In this project, we aim to identify novel inborn errors of immunity conferring increased susceptibility to recurrent lymphocytic Mollaret’s meningitis caused by herpes simplex virus 2. By using advanced methodological approaches, including whole exome sequencing, genome editing and disease-mimicking model systems, we will search for key mechanisms of importance for antiviral defense. This project will provide new insights that can be translated into early genetic diagnosis, prophylaxis and gene therapy, and may pave the way for development of new antiviral therapies.
Beneficiaries (1)
| Organisation | Country | Role | EC contribution | SME |
|---|---|---|---|---|
| AARHUS UNIVERSITET | DK | coordinator | €230,774 |
Get the DFM funding briefing — free
New EU defence calls, tenders and awards in your inbox.
Defence Finance Monitor is an analytical and informational product. Grant data is official CORDIS; payment and subscription happen on DFM Analysis.