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4D Microscopy of biological materials by short pulse terahertz sources (MIMOSA)broad

MIMOSA · Horizon Europe grant · 2022-09-01–2026-08-31

EC contribution

€3,591,780

Total cost

€3,591,780

Beneficiaries

11
About the data

Source: CORDIS (official EU open data), Horizon Europe. Framework HORIZON · call HORIZON-EIC-2021-PATHFINDEROPEN-01 · scheme HORIZON-EIC · topic HORIZON-EIC-2021-PATHFINDEROPEN-01-01. CORDIS record →

Objective

Cryo-electron microscopy and tomography have been among the greatest achievements in biological imaging, but these techniques suffer from insufficient chemical resolution.The ultimate goal of MIMOSA is to provide an alternative to tomography at the nanoscale with a high chemical resolution for biological and medical systems, based on Tomographic Atom Probe (TAP).MIMOSA aims to prototype a new TAP triggered by intense terahertz (THz) pulses that are stable at high repetition rates and exhibit versatile and tailored properties.MIMOSA relies on the integration of trans-disciplinary fields in bio-imaging, optics, ultrafast lasers and intense THz sources, big-data treatment and physics of the interaction between THz waves and matter.MIMOSA aims to prototype in parallel an efficient intense THz source based on a new technology with ultrafast high-energy fiber lasers. This source can be used in nano-tomography for biological and medical applications but also as a test platform for a foreseeable commercialization of the THz-triggered TAP.The MIMOSA team members are leaders in TAP development, 3D medical and bio-imaging, ultrafast lasers development with advanced techniques for shaping and control of the optical beam’s properties and theoretical physics. With MIMOSA we are uniquely positioned to succeed and to raise the competitiveness of Europe in microscopy development on the international scene.

Beneficiaries (11)

OrganisationCountryRoleEC contributionSME
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR coordinator €1,415,589
INSTITUTUL NATIONAL DE CERCETAREDEZVOLTARE PENTRU MICROTEHNOLOGIE RO participant €450,000
ACTIVE FIBER SYSTEMS GMBH DE participant €399,812 Yes
CHALMERS TEKNISKA HOGSKOLA AB SE participant €382,900
CONSIGLIO NAZIONALE DELLE RICERCHE IT participant €326,642
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE FR participant €310,386
FONDAZIONE BRUNO KESSLER IT participant €306,450
UNIVERSITA DEGLI STUDI DI TRENTO IT thirdParty €0
UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II IT thirdParty €0
UNIVERSITE DE ROUEN NORMANDIE FR thirdParty €0
ECOLE DE TECHNOLOGIE SUPERIEURE CA associatedPartner

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